Do you love the "locate" tool on Linux and wish your Windows box had the same capabilities? If so, check out Invoke-Locate, a PowerShell script written by Chrissy LeMaire. It builds a SQLlite database (can use a MSSQL DB if you prefer) of files on all local disks, can index mounted drives (careful with that option in a corporate environment), and includes an option to "install" which creates a scheduled task to update the DB every 6 hours.
I would recommend the install option if you can spare the CPU cycles, as manually running the updatedb command takes a few minutes; but subsequent searching using the locate command are lightning quick (far faster than Windows' built-in search even with indexing enabled.) As always, check the help and example sections of the script for details and a slew of options.
Links:
Chrissy's blog entry announcing the script.
ScriptCenter download page.